James Irrgang holds secondary appointments in the Department of Orthopedic Surgery and the Clinical and Translational Science Institute in the School of Medicine. Currently, Irrgang serves as the Scientific Director of the American Physical Therapy Association's Physical Therapy Outcomes Registry. His research interests include development and validation of patient-reported outcome measures as well as clinical research related to the knee and shoulder. Current active studies include: 1) a study to provide validity evidence for the PROMIS pain interference and physical function computer adaptive tests (CATs) for individuals with a variety of knee conditions and 2) a prospective observational study to determine the outcome and factors influencing the effects of exercise therapy for individuals with a full-thickness supraspinatus tear. Additionally, he is leading a team to plan a multicenter clinical trial to determine the effects of timing of surgery (early vs. delayed) and post-operative rehabilitation (early vs. delayed) for the treatment of multiple ligament knee injuries. Irrgang served as President of the Orthopaedic Section from 2007 to 2013 and was presented with the Paris Distinguished Service Award from the Section in 2015.